Fibrosarcoma
Description of the Disease and Clinical Picture
Fibrosarcoma is a malignant tumor that arises from fibroblasts (connective tissue cells). It is a slow-growing tumor that rarely metastasizes but is extremely locally invasive. When found on the eyelids, in many cases, it also affects the eyeball and the eye socket (orbit). The tumor presents as a subcutaneous swelling, firm to the touch and poorly movable, and may sometimes have an ulcerated surface. It is more common in large dog breeds of middle age - such as Golden Retrievers, Dobermans, and Rottweilers. It's a common tumor in older cats but can sometimes appear in younger cats as well, and it is suspected to possibly be a consequence of a feline leukemia virus mutation.
 
Therapy
Fine-needle aspiration can be performed, and a preliminary diagnosis can be made by examining the aspirate. The definitive diagnosis is made by histopathological examination of the tumor after surgical removal, determining the degree of malignancy as well. The higher the mitotic activity, the more malignant the tumor is. X-rays, CT, and MRI scans are used to determine the invasiveness of the change and detect metastases. Due to its tendency to recur, the therapy is aggressive and involves removal of the tumor and surrounding tissue along with radiation therapy and/or chemotherapy.
 
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